Too much paracetamol = dangerous because of how your liver processes it. *Normal dose:* About 90 95% gets broken down safely by glucuronidation + sulfation non toxic stuff you pee out. *The problem Acute acetaminophen paracetamol toxicity Acetaminophen or Tylenol Toxicity Lect 19 Pharmacology TYLENOL [Acetaminophen] metabolism A lot of GLUTATHIONE is needed to deal with the Oxidative Stress generated by the CYP 450 metabolism of Tylenol. When people go to the ER for Tylenol Overdose
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paracetamol and glutathione depletion Paracetamol poisoning