Acetaminophen Toxicity: How Genetic Susceptibility Combines with Environmental Factors Tylenol (acetaminophen) does not cause autism. The FDA, in its statement that there may be an association, confirmed that "a causal relationship has not been established, and studies of millions of children Fact Check: Can Tylenol Cause Autism? Acetaminophen causes neurodevelopmental injury in susceptible babies and children: no valid rationale for controversy