How to Give Yourself Intramuscular (IM) Injections Patients & Families UW Health Subcutaneous Injection: What It Is and How to Give One B12 Shots at Home: How, Where & How Often to Inject Yourself AZ IV Medics Injection Techniques Step by Step Guide 1. Intramuscular Injection (IM) 90 Angle Needle Position: Perpendicular to the skin (90 angle) Target Site: Muscle layer Common Sites: Deltoid, Vastus Lateralis,