Melanotic macule on the lower lip Download Scientific Diagram Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Oral melanoacanthoma and oral melanotic macule: a report of 8 cases, review of the literature, and immunohistochemical analysis Congenital Melanotic Macules of the Tongue The Journal of Pediatrics